(EMAILWIRE.COM, October 14, 2009 ) Dallas, TX - BioCryst Pharmaceuticals, Inc. (NASDAQ:BCRX) was among the top percentage gainer and surged 7.34% to $8.92 on over 1.72 million shares after a JMP Securities analyst initiated coverage with an "Outperform" rating, citing revenue potential for the company's flu treatment peramivir and cancer drug forodesine. BioCryst Pharmaceuticals, Inc. (BioCryst) is a biotechnology company that designs, optimizes and develops drugs that block enzymes involved in cancer, viral infections and autoimmune diseases.

AVI BioPharma, Inc. (NASDAQ:AVII) gained 4.52% and the last traded price was $1.85 with a total traded quantity of over 2.13 million shares. AVI BioPharma, Inc. (AVI) is a biopharmaceutical company specializing in the discovery and development of ribonucleic acid (RNA)-based drugs targeting a range of diseases. The Company has developed and optimized derivatives of its antisense chemistry (phosphorodiamidate morpholino oligomers (PMOs)) that can be designed to target disease mechanisms through mechanisms of action.

Sapient Corporation (NASDAQ:SAPE) was among the percentage movers. The stock increased over 6.72% and closed at $8.58 with over 2.59 million shares being traded. Stifel Nicolaus analyst George Price upped his rating on the stock to Buy from Hold, setting a price target of $10. Sapient Corporation (Sapient), is a global services firm. The Company markets its services through two primary areas of focus: Sapient Interactive and Sapient Consulting. Sapient Interactive is an interactive marketing agency, which provides brand and marketing strategy, creative work, Web design and development and emerging media expertise.

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