Research Shows Caprylic Triglyceride Could Reduce The Symptoms Of A Incurable Muscle Wasting Disease
Does coconut oil offer hope for ALS?
However, scientists believe that focusing on improving mitochondrial function could be an effective way to help manage some of the symptoms of this incurable condition. During the research, which was published in the PLoS One journal, scientists set out to discover if a ketogenic diet could help preserve muscle function.
The trial was conducted using mice; they were regularly tested for motor function. At the conclusion of the study it was shown that the animals that were fed caprylic acid in the form of caprylic triglyceride had less muscle wastage, and they also had a longer survival rate.
In addition, it was found that caprylic triglyceride safely increased the ketone levels and that the mice fed caprylic triglyceride lost fewer motor neurones. Overall, the animals that were fed caprylic triglyceride showed a "significant improvement" in the clinical symptoms of ALS and motor neuron survival was also improved.
The caprylic acid in coconut oil is a rich source of medium-chain triglycerides; a ketogenic diet has been shown to be effective in other neurodegenerative diseases such as Parkinson's disease.
It is hoped that by using ketones as an alternative energy source for the body, this could help reduce the symptoms of ALS and prolong survival. However, there is more research needed into this area, but the study indicated that there is a justification for further research to see if using caprylic triglyceride would have the same effect on humans suffering from ALS.
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Zhao W, Varghese M, Vempati P, Dzhun A, Cheng A, et al. (2012) Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease. PLoS ONE 7(11): e49191. doi:10.1371/journal.pone.0049191
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